|January 6, 2006|
|Olympus Corporation (President: Tsuyoshi Kikukawa) has concluded the expansion of its ongoing research collaboration with Cangen Biotechnologies, Inc. (Maryland, USA; CEO: Chul So Moon, M.D., Ph.D., President: Richard A. Silfen), initiated in May 2005, to develop a hybrid DNA-based and protein-based diagnostic test for use in the early detection of lung cancer. The expanded collaboration includes funding for a prospective clinical study.|
|The goal of this research collaboration is the establishment of a blood-based molecular diagnostic test for early detection of lung cancer. The identification of specific DNA markers is underway. Several key DNA marker candidates with 70-80% accuracy have been identified from preserved surgically resected samples obtained by Cangen from Hyundai Hospital in Korea. These markers can be used as a hybrid with protein-based markers to improve sensitivity and specificity. In the next step, beginning this spring, the collaboration will be expanded to evaluate and finalize the DNA markers through a prospective study in Asia. Olympus and Cangen are aiming for FDA approval after approximately two years.|
|Olympus has been a participant since December 2002 in the activities of Cosmos Alliance (http://www.cosmosalliance.com, Washington D.C., USA; Chairman & CEO: Prof. Frank Young), an international alliance formed to accelerate commercialization in the bio life sciences through equity investments, joint ventures, collaborative research and technology transfer. Through Cosmos-facilitated joint development programs, technical cooperation programs and capital investment into the Technical- and R&D-Members within the Cosmos Bio Life Sciences Alliance that possess innovative biotech expertise, Olympus plans to accelerate the commercialization of its own range of advanced biotech-related products, which includes instruments for genome and protein analysis. This research collaboration with Cangen Biotechnologies represents one of these efforts.|
|Overview of Cangen Biotechnologies|
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